| Phone: | +49-3641-949580 |
|---|---|
| Fax: | +49-3641-946452 |
| E-Mail: | Stefan.Schu@uni-jena.de |
Stefan Schuster (Group Leader)
The Schuster Group has ample experience in metabolic pathway analysis for more than a decade. In particular, modelling of E. coli and hepatocyte metabolisms has been part of projects within the Jena Centre for Bioinformatics (JCB) and still is part of several Systems Biology programs funded by BMBF. The concept of elementary flux modes proposed by the group is applied by numerous groups worldwide. Moreover, the Schuster Group is active in several other fields such as the mathematical modelling of intracellular calcium oscillations, evolutionary game theory and alternative splicing. The book "The Regulation of Cellular Systems" (1996) by Heinrich and Schuster is a pioneering monograph in systems biology.
For more information look at the Bioinformatics Group page of the Friedrich Schiller University (FSU).
Ruppin E, Papin JA, de Figueiredo LF, Schuster S:
Metabolic reconstruction, constraint-based analysis and game theory to probe genome-scale metabolic networks.
Curr Opin Biotechnol.
2010;
21:502-10.
Hummert S, Hummert C, Schröter A, Hube B, Schuster S:
Game theoretical modelling of survival strategies of Candida albicans inside macrophages.
J Theor Biol.
2010;
264:312-8.
Kaleta C, de Figueiredo LF, Schuster S:
Can the whole be less than the sum of its parts? Pathway analysis in genome-scale metabolic networks using elementary flux patterns.
Genome Res.
2009;
19:1872-83.
de Figueiredo LF, Schuster S, Kaleta C, Fell DA:
Can sugars be produced from fatty acids? A test case for pathway analysis tools.
Bioinformatics.
2009;
25:152-8.
Schuster S, Pfeiffer T, Fell DA:
Is maximization of molar yield in metabolic networks favoured by evolution?.
J Theor Biol.
2008;
252:497-504.